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Chemopreventive Agent Development Research Group

Publications and Presentations

Clinical Development Plans

Kelloff, G.J., Crowell, J.A., Hawk, E.T., Steele, V.E., Lubet, R.A., Boone, C.W., Covey, J.M., Doody, L.A., Omenn, G.S., Greenwald, P., Hong, W.K., Parkinson, D.R., Bagheri, D., Baxter, G.T., Blunden, M., Doeltz, M.K., Eisenhauer, K.M., Johnson, K., Knapp, G.G., Longfellow, D.G., Malone, W.F., Nayfield, S.G., Seifried, H.E., Swall, L.M. and Sigman, C.C. (1996) Strategy and planning for chemopreventive drug development: Clinical development plans II. J. Cell. Biochem. Suppl. 26: 54--71.

Title	Pages
Overview	54-71
Curcumin	72-85
Dehydroepiandrosterone (DHEA)	86-99
Folic acid	99-113
Genistein	114-126
Indole-3-carbinol	127-136
Perillyl alcohol	137-148
Phenethylisothiocyanate (PEITC)	149-157
9-cis-Retinoic acid	158-167
13-cis-Retinoic acid	168-201
l-Selenomethionine	202-218
1,4-Phenylenebis(methylene) and Selenocyanate (p-XSC)	219-226
Sulindac sulfone	227-235
Tea extracts, green tea polyphenols, and Epigallocatechin gallate	236-257
Ursodiol	258-268
Vitamin A	269-306
(+)-Vorozole	307-315

Kelloff, G.J., Crowell, J.A., Boone, C.W., Steele, V.E., Lubet, R.A., Greenwald, P., Alberts, D.S., Covey, J.M., Doody, L.A., Knapp, G.G., Nayfield, S., Parkinson, D.R., Prasad, V.K., Prorok, P.C., Sausville, E.A. and Sigman, C.C. Strategy and planning for chemopreventive drug development: Clinical development plans I. J. Cell. Biochem. Suppl. 20: 55-299, 1994:

Title	Pages
Overview	55-62
N-Acetyl-l-cysteine	63-73
Aspirin	74-85
Calcium	86-109
Carotene and other carotenoids	110-140
DHEA analog 8354	141-146
2-Difluoromethylornithine (DFMO)	147-165
18 -Glycyrrhetinic acid	166-175
N-(4-Hydroxyphenyl)retinamide	176-196
Ibuprofen	197-204
Oltipraz	205-218
Piroxicam	219-230
Proscar	231-239
Sulindac	240-251
Tamoxifen	252-267
Vitamin D3 and analogs	268-281
Vitamin E	282-299