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Chemopreventive Agent Development Research Group

Publications and Presentations

Clinical Development Plans

Kelloff, G.J., Crowell, J.A., Hawk, E.T., Steele, V.E., Lubet, R.A., Boone, C.W., Covey, J.M., Doody, L.A., Omenn, G.S., Greenwald, P., Hong, W.K., Parkinson, D.R., Bagheri, D., Baxter, G.T., Blunden, M., Doeltz, M.K., Eisenhauer, K.M., Johnson, K., Knapp, G.G., Longfellow, D.G., Malone, W.F., Nayfield, S.G., Seifried, H.E., Swall, L.M. and Sigman, C.C. (1996) Strategy and planning for chemopreventive drug development: Clinical development plans II. J. Cell. Biochem. Suppl. 26: 54--71.

TitlePages
Overview54-71
Curcumin72-85
Dehydroepiandrosterone (DHEA)86-99
Folic acid99-113
Genistein114-126
Indole-3-carbinol127-136
Perillyl alcohol137-148
Phenethylisothiocyanate (PEITC)149-157
9-cis-Retinoic acid158-167
13-cis-Retinoic acid168-201
l-Selenomethionine202-218
1,4-Phenylenebis(methylene) and Selenocyanate (p-XSC)219-226
Sulindac sulfone227-235
Tea extracts, green tea polyphenols, and Epigallocatechin gallate236-257
Ursodiol258-268
Vitamin A269-306
(+)-Vorozole307-315

Kelloff, G.J., Crowell, J.A., Boone, C.W., Steele, V.E., Lubet, R.A., Greenwald, P., Alberts, D.S., Covey, J.M., Doody, L.A., Knapp, G.G., Nayfield, S., Parkinson, D.R., Prasad, V.K., Prorok, P.C., Sausville, E.A. and Sigman, C.C. Strategy and planning for chemopreventive drug development: Clinical development plans I. J. Cell. Biochem. Suppl. 20: 55-299, 1994:

TitlePages
Overview55-62
N-Acetyl-l-cysteine63-73
Aspirin74-85
Calcium86-109
Carotene and other carotenoids110-140
DHEA analog 8354141-146
2-Difluoromethylornithine (DFMO)147-165
18 -Glycyrrhetinic acid166-175
N-(4-Hydroxyphenyl)retinamide176-196
Ibuprofen197-204
Oltipraz205-218
Piroxicam219-230
Proscar231-239
Sulindac240-251
Tamoxifen252-267
Vitamin D3 and analogs268-281
Vitamin E282-299


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