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Chemopreventive Agent Development Research Group

Publications and Presentations

Clinical Development Plans

Kelloff, G.J., Crowell, J.A., Hawk, E.T., Steele, V.E., Lubet, R.A., Boone, C.W., Covey, J.M., Doody, L.A., Omenn, G.S., Greenwald, P., Hong, W.K., Parkinson, D.R., Bagheri, D., Baxter, G.T., Blunden, M., Doeltz, M.K., Eisenhauer, K.M., Johnson, K., Knapp, G.G., Longfellow, D.G., Malone, W.F., Nayfield, S.G., Seifried, H.E., Swall, L.M. and Sigman, C.C. (1996) Strategy and planning for chemopreventive drug development: Clinical development plans II. J. Cell. Biochem. Suppl. 26: 54--71.

Title Pages
Overview 54-71
Curcumin 72-85
Dehydroepiandrosterone (DHEA) 86-99
Folic acid 99-113
Genistein 114-126
Indole-3-carbinol 127-136
Perillyl alcohol 137-148
Phenethylisothiocyanate (PEITC) 149-157
9-cis-Retinoic acid 158-167
13-cis-Retinoic acid 168-201
l-Selenomethionine 202-218
1,4-Phenylenebis(methylene) and Selenocyanate (p-XSC) 219-226
Sulindac sulfone 227-235
Tea extracts, green tea polyphenols, and Epigallocatechin gallate 236-257
Ursodiol 258-268
Vitamin A 269-306
(+)-Vorozole 307-315

Kelloff, G.J., Crowell, J.A., Boone, C.W., Steele, V.E., Lubet, R.A., Greenwald, P., Alberts, D.S., Covey, J.M., Doody, L.A., Knapp, G.G., Nayfield, S., Parkinson, D.R., Prasad, V.K., Prorok, P.C., Sausville, E.A. and Sigman, C.C. Strategy and planning for chemopreventive drug development: Clinical development plans I. J. Cell. Biochem. Suppl. 20: 55-299, 1994:

Title Pages
Overview 55-62
N-Acetyl-l-cysteine 63-73
Aspirin 74-85
Calcium 86-109
Carotene and other carotenoids 110-140
DHEA analog 8354 141-146
2-Difluoromethylornithine (DFMO) 147-165
18 -Glycyrrhetinic acid 166-175
N-(4-Hydroxyphenyl)retinamide 176-196
Ibuprofen 197-204
Oltipraz 205-218
Piroxicam 219-230
Proscar 231-239
Sulindac 240-251
Tamoxifen 252-267
Vitamin D3 and analogs 268-281
Vitamin E 282-299


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