Publications and Presentations
Journal Articles
2006
Claudine Kavanaugh, Harold Seifried, Kathleen Ellwood, Elizabeth Yetley , Christine Swanson, John Milner (2006) A research agenda for biomarkers as indicators of cancer risk reduction following dietary manipulation Journal of Nutrition (submitted June).
Cope, K.A.; Milner, J.; Seifried, R.M.; Seifried, H.E.; Harrison, E.H. (2006). Effects of garlic ingestion in humans on the formation of urinary nitrosoproline in humans Journal of Nutritional Biochemistry (submitted July).
Davis C. Mechanisms for the cancer protective effects of bioactive dietary components in fruits and vegetables. In Handbook of Nutrition and Food (2nd ed.). In press.
Davis C. Nutritional pre-emption: credentialing of molecular targets for cancer prevention. Experimental Biology and Medicine. In Press.
Davis, C.D. and Milner, J.A. Evolving 'omics' approaches for elucidating the role of selenium and selenoproteins in cancer prevention, In: Selenium: Its Molecular Biology and Role in Human Health, in press.
Emenaker N., Milner J. Eating for cancer prevention. Agro Food industry hi-tech. 17(3):24-26, 2006.
Honnig B., Ettinger A., Jandacek R., Hoo S., McClain C., Seifried H., Silverstone A., Watkins B., Thompson C., Sak W. Using nutrition for intervention and protection against environmental chemical toxicity and associated diseases. Journal of Nutritional Biochemistry. In press.
Irons R., Carlson B.A., Hatfield, D.L. and Davis C.D.. Both selenoproteins and low molecular weight selenocompounds reduce colon cancer risk in mice with genetically impaired selenoprotein expression. J Nutr. 2006 May;136(5):1311-7.
Kavanaough C., Seifried H., Ellwood K., Yetley E., Swanson C., Milner J. A research agenda for biomarkers as indicators of cancer risk reduction following dietary manipulation. J Nutr. 2006; 136(10S); 2666S-7S.
Milner J. Diet and cancer: facts and controversies. Nutrition and Cancer. In press.
Milner J.A.. Preclinical perspectives on garlic and cancer. J Nutr. 2006 Mar;136(3 Suppl):827S-831S.
Pogribny I., Ross S.A., Tryndyak V.P., Progribna M., Poirer L.A., Karpinets T.V.. Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats. Carcinogenesis. 2006 Jun;27(6):1180-6.
Pogribny I., Ross S.A., Wise C., Progribna M., Jones E.A., Tryndyak V.P., James S.J., Dragan Y.P., Poirer L.A. Irreversible global DNA hypomethylation as a key step in hepatocarcinogenesis induced by dietary methyl deficiency. Mutat Res. 2006 Jan 29;593(1-2):80-7.
Ross S.A., Finley J.W., Milner J.A.. Allyl sulfur compounds from garlic modulate aberrant crypt formation. J Nutr. 2006 Mar;136(3 Suppl):852S-854S.
Ross S., Milner J. Garlic: the mystical food in health promotion. In Baer, Dubowska, Bartoszek, Malejka-Giganti (eds.), Handbook of Neutraceuticals and Functional Foods (2nd ed). Taylor and Francis Group. In press.
Seifried, H.E. (2006) Oxidative Stress and Antioxidants: a link to disease and prevention? J Nutr Biochem. In press.
Seifried H., Anderson D., Fisher E., Milner J., (2006) A Review of the Interaction Among Dietary Antioxidants and Reactive Oxygen Species. J Nutr Biochem. In press.
Seifried H., Anderson A., Milner J., Greenwald P. (2006) Reactive Oxygen Species and Dietary Antioxidants:Double-Edged Swords?, New Developments in Antioxidant Research. Hauppauge, NY: Nova Science Publishers, Inc.
Seifried H.E., Seifried R.M., Clarke J.J., Junghans T.B., San R.H. A compilation of two decades of mutagenicity test results with the Ames Salmonella typhimurium and L5178Y mouse lymphoma cell mutation assays. Chem Res Toxicol. 2006 May;19(5):627-44.
Takahashi Y., Lavigne J.A., Hursting S.D., Chandramouli G.V., Perkins S.N., Kim Y.S., Wang T.T. Molecular signatures of soy_derived phytochemicals in androgen_responsive prostate cancer cells: A comparison study using DNA microarray. Mol Carcinog.[Epub ahead of print], 2006.
Trujillo E., Davis C., Milner J. Nutrigenomics, proteomics, metabolomics, and the practice of dietetics. J Am Diet Assoc. 2006 Mar;106(3):403-13.
Trujillo E.B., Nebeling L. Carbohydrates, Protein and Fat Metabolism. In: Ellicott L, Molseed L, Davis McCallum P, Grant B (eds). The Clinical Guide to Oncology Nutrition. Chicago, IL: American Dietetic Association Publishers, 2006.
Tryndyak V., Kovalchuk L., Montgomery B., Rodriquez-Juarez S., Melnyk S., Ross S., Beland F., Pogribny I. Epigenetic reprogramming of liver cells in tamoxifen-induced rat hepatocarcinogenesis. Molecular Carcinogenesis. In press.
Tryndyak VP., Muskhelishvili L., Kovalchuk O., Rodriquez-Juarez R., Montgomery B., Churchwell M.I., Ross S.A., Beland F., Pogribny I. Effect of long-term tamoxifen exposure on genotoxic and epigenetic changes in rat liver: implications for tamoxifen-induced hepatocarcinogenesis. Carcinogenesis. 2006 Aug;27(8):1713-20.
Uthus E.O., Ross S.A., Davis C.D.. Differential effects of dietary selenium (se) and folate on methyl metabolism in liver and colon of rats. Biol Trace Elem Res. 2006 Mar;109(3):201-14.
Wang T.T., Milner M.J., Milner J.A., Kim Y.S. Estrogen receptor alpha as a target for indole-3-carbinol. J Nutr Biochem. 2006 Oct;17(10):659-64.
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2005
Clarke, J.J., Whittaker, P.,San,R.H.C. Seifried, H.E., and Dunkel,V.C., 2005 "Mutagenicity Of Chromium Picolinate And Its Components In Salmonella Typhimurium and L5178Y Mouse Lymphoma Cells" Abstract - Environmental Mutagen Society Environmental and Molecular Mutagenesis September (San Francisco, CA).
Davis, C.D., Clevidence, B., Swanson, C.A., Ziegler, R.G., Dwyer, J.T. and Milner, J.A. A research agenda for lycopene/tomato supplementation and cancer prevention. J. Nutr., 135: 2074s, 2005.
Davis, C.D. and Hord, N.G. Nutritional 'Omics' Technologies for Elucidating the Role(s) of Bioactive Food Components in Colon Cancer Prevention. J. Nutr., 135: 2694-2697, 2005.
Davis, C.D. and Irons, R. Are selenoproteins important for the cancer protective effects of selenium? Current Nutrition Reviews, 1: 201-214, 2005.
Davis, C.D. and Milner, J.A. Diet and cancer prevention, In: 2nd Edition of Nutrition in Health, Humana Press Inc., pp. 151-171, 2005.
Davis, C.D., Swanson, C.A., Ziegler, R.G., Clevidence, B., Dwyer, J.T. and Milner, J.A. Executive summary report. J. Nutr., 135: 2014s-2029s, 2005.
Kaput, J. Ordovas, J.M., Ferguson, L., van Ommen, B., Rodriguez, R.L., Allen, L., Ames, B.N., Dawson, K., German, B., Krauss, R., Malyj W., Archer, M.C., Barnes, S., Bartholomew, A., Birk, R., van Bladeren, P., Bradford, K.J., Brown, K.H., Caetano, R., Castle, D., Chadwick, R., Clarke, S., Clement, K., Cooney, C.A., Corella, D., Manica da Cruz, I.B., Daniel, H., Duster, T., Ebbesson, S.O.E., Elliott, R., Fairweather-Tait S., Felton J., Fenech, M., Finley, J.W., Fogg-Johnson, N., Gill-Garrison, R., Gibney, M. J., Gillies, P.J., Gustafsson, J.A., Hartman IV, J.L., He, L., Hwang, J.-K., Jais, J.-P., Jang, Y., Joost, H., Junien, C., Kanter, M., Kibbe, W.A., Koletzko, B., Korf, B.R., Kornman, K., Krempin, D.W., Langin, D., Lauren, D.R., Lee, J.H., Leveille, G.A., Lin, S.-J., Mathers, J., Mayne, M., McNabb, W., Milner, J.A., Morgan, P., Muller, M., Nikolsky, Y., van der Ouderaa, F., Park, T., Pensel, N., Perez-Jimenez, F., Poutanen, K., Roberts, M., Saris, W.H.M., Schuster, G., Shelling, A.N., Simopoulos, A.P., Southon, S., Tai, E.S., Towne, B., Trayhurn, P., Uauy, R., Visek, W.J., Warden, C., Weiss, R., Wiencke, J., Winkler, J., Wolff, G.L., Zhao-Wilson, X., Zucker, J.-D. The case for strategic international alliances to harness nutritional genomics for public and personal health. Br J Nut, 2005 Nov; 94(5), 623-632.
Kim, YS and Milner, JA. Targets for indole-3-carbinol in cancer prevention. J Nutr Biochem. 16:65-73, 2005.
Percival SS, Nelson SA, Milner JA. Workshop executive summary report. J Nutr. 2005 Dec;135(12):2898S-2920S.
Percival SS, Milner JA. Opportunities for research. J Nutr. 2005 Dec;135(12):2921S-2923S.
Pervical SS, Milner, JA. Challenges and opportunities for support of nutritional science conferences and scientific meetings at National Institutes of Health.
J Nutr. 2005 Aug;135(8):2006-8.
Smeltzer, A and Kim, YS. The Effects of Bioactive Food Components on p53 Pathway in Cancer Prevention. Nutrition Today, 40: 50-53, 2005.
Uthus, E.O. and Davis, C.D. Dietary arsenic affects dimethylhydrazine-induced aberrant crypt formation and hepatic global DNA methylation and DNA methyltransferase activity Biol. Trace Element Res., 103: 133-145, 2005.
Wang TT, Milner MJ, Milner JA, Kim YS. Estrogen receptor alpha as a target for indole-3-carbinol. J Nutr Biochem. 2006 Oct;17(10):659-64. Epub 2005 Nov 28.
Whittaker, P.,Dunkel,V.C.,, Seifried, H.E., San,R.H.C. and Clarke, J.J. 2005 "Mutagenicity Of Chromium Picolinate And Its Components In Salmonella Typhimurium and L5178Y Mouse Lymphoma" Abstract - Association of Official Analytical Chemists Annual meeting September (Orlando Florida).
Whittaker P, San RH, Clarke JJ, Seifried HE, Dunkel VC. Mutagenicity of chromium picolinate and its components in Salmonella typhimurium and L5178Y mouse lymphoma cells. Food Chem Toxicol. 2005 Nov;43(11):1619-25.
Zeisel SH, Freake HC, Bauman DE, Bier DM, Burrin DG, German JB, Klein S, Marquis GS, Milner JA, Pelto GH, Rasmussen KM. The nutritional phenotype in the age of metabolomics. J Nutr. 2005 Jul;135(7):1613-6.
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2004
Debski B., Milner J.A. Dietary selenium supplementation prolongs pentobarbital induced hypnosis. J Nutr Biochem. 2004 Sep;15(9):548-53.
Davis, C.D. and Milner, J.A. Frontiers in Nutrigenetics, Nutrigenomics, Proteomics, Metabolomics and Cancer Prevention. Mutat. Res., 551: 51-64, 2004.
Davis, C.D. and Uthus, E.O. Nutrient interactions, DNA methylation and cancer susceptibility. Exp. Biol. Med., 229: 988-995, 2004.
German J.B., Bauman D.E., Burrin D.G., Failla M.L., Freake H.C., King J.C., Klein S., Milner J.A., Pelto G.H., Rasmussen K.M., Zeisel S.H. Metabolomics in the opening decade of the 21st century: building the roads to individualized health. J Nutr. 2004 Oct;134(10):2729-32.
Junghans, T.B., Sevin, I.F., Ionin, B and Seifried H 2004 "Cancer Information Resources: Digital and Online Sources" Toxicology 198:177-93.
Milner JA. Molecular targets for bioactive food components. J Nutr. 2004 Sep;134(9):2492S-2498S. Review. PMID: 15333748 [PubMed - indexed for MEDLINE].
Rosenfeld S., Wang T., Kim Y., and Milner J. Numerical Deconvolution of cDNA Microarray Signal: Simulation Study. Ann. N.Y. Acad. Sci. 1020:110-123, 2004.
Ross, S.A., Srinivas, P.R., Clifford, A.J., Lee, S.C., Philbert, M.A., Hettich, R.L. New technologies for nutrition research. J Nutr.134:681-5, 2004.
Seifried, H.E., Anderson, D.E., Sorkin, B.C., Costello, R.B. 2004 "Free radicals: the pros and cons of antioxidants. Executive summary report." J Nutr.;134:3143S-3163S.
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2003
Davis, C.D. Can Exfoliated Cells Be Useful For Predicting Responses To Bioactive Food Components in Cells of Target Tissues? J. Nutr., 133: 1769-1772, 2003.
Davis, C.D. Low dietary copper increases fecal free radical production and fecal water alkaline phosphatase activity and cytotoxicity in healthy men. J. Nutr., 133: 522-527, 2003.
Davis, C.D. Selenium and cancer prevention. In: Beneficial Effect of Selenium on Cancer Prevention and Health. Korean Assoc. Cancer Res., pp. 42-56, 2003.
Davis, C.D. and Finley, J.W. Chemical versus food forms of selenium in cancer prevention. In: Functional Foods and Nutraceuticals in Cancer Prevention and Treatment. Iowa State University Press, pp. 55-85, 2003.
Davis, C.D. and Uthus, E.O. Dietary folate and selenium affect dimethylhydrazine-induced aberrant crypt formation, global DNA methylation and one-carbon metabolism in rats. J. Nutr., 133: 2907-2914, 2003.
Davis, C.D. and Uthus, E.O. Does dietary selenium affect plasma homocysteine concentrations in humans? J. Nutr., 133: 2392 (letter).
Finley, J.W., Penland, J.G., Petit, R.E. and Davis, C.D. Dietary Manganese Intake and Lipid Source Alter Manganese Absorption and Retention But Do Not Affect Clinical or Neuropsychological Measures in Healthy Young Women. J. Nutr., 133: 2849-2856, 2003.
Hine, R.J., Srivastava, S., Milner, J.A. and Ross, S.A.: Nutritional links to plausible mechanisms underlying pancreatic cancer: a conference report. Pancreas. 27:356-66, 2003.
Kim, YS and Milner JA. Nutritional Genomics and Proteomics in Cancer Prevention: Introduction. J Nutr. 133(7 Suppl):2399S, 2003.
Ross, S.A.: Diet and DNA Methylation Interactions in Cancer Prevention. Ann NY Acad Sci. 983:197-207, 2003.
Seifried, H.E., McDonald, S.S., Anderson, D.E., Greenwald, P, Milner, J.A. 2003 "The Antioxidant Conundrum in Cancer" Cancer Research August 63(15):4295_8.
Verma, M., Dunn, B.K., Ross, S., Jain, P., Wang, W., Hayes, R. and Umar, A.: Early detection and risk assessment: proceedings and recommendations from the Workshop on Epigenetics in Cancer Prevention. Ann N Y Acad Sci. 983:298-319, 2003.
Zeng, H.E. and Davis, C.D. Down-regulation of the PCNA gene expression occurs during cell cycle arrest induced by human fecal water in colonic HT-29 cells. J. Nutr., 133: 2682-2687, 2003.
Zeng, H., Davis, C.D. and Finley, J.W. Effect of selenium-enriched broccoli diet on differential gene expression in min mouse liver. J. Nutrl. Biochem., 14: 227-231, 2003.
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2002
Banuelos, G.S., Vickerman, D.B., Trumble, J.T., Shannon, M.C., Davis, C.D., Finley, J.W. and Mayland, H.F. Biotransfer possibilities of selenium from plants used in phytoremediation. Int. J. Phytoremediation., 4: 315-329, 2002.
Davis, C.D. and Johnson, W.T. Dietary Copper Affects Azoxymethane-Induced Intestinal Tumor Formation and Protein Kinase C Isozyme Protein and mRNA Expression in Colon of Rats. J. Nutr., 132: 1918-1025, 2002.
Davis, C.D. and Uthus, E.O. Dietary Selenium and Azadeoxycytidine Treatment Affect Dimethylhydrazine-Induced Aberrant Crypt Formation in Rat Colon and DNA Methylation in HT-29 Cells. J. Nutr. , 132: 292-297, 2002.
Davis, C.D., Zeng, H. and Finley, J.W. Selenium-Enriched Broccoli Decreases Intestinal Tumorigenesis in Multiple Intestinal Neoplasia (Min) Mice. J. Nutr., 132: 307-309, 2002.
Harbell, J., Dunkel, V.C., San, R., Seifried, H.E., and Cameron, T.P. 2002 "Gentoxicity of Naphthenate Salts in the Salmonella/Mammalian-Microsome Assay and Mouse Lymphoma TK+/- Assay" Mutation Research (in Press).
Junghans, T.J., Sevin, I.F., Ionin, B. and Seifried, H. 2002 "Cancer Information Resources: Digital and Online Sources" Toxicology 173:13-34.
Ross, S.A. and Poirier, L.: Proceedings of the Trans-HHS Workshop: Diet, DNA Methylation Processes and Health. J Nutr. 132:2329S-32S, 2002.
Uthus, E.O., Yokoi, K. and Davis, C.D. Selenium deprivation in Fischer-344 rats results in decreased plasma and tissue homocysteine concentrations and an altered plasma homocysteine and cysteine redox status. J. Nutr., 132: 1122-1128, 2002.
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2001
Davis, C.D. and Johnson, W.T. Dietary copper and dimethylhydrazine affect protein kinase C protein and mRNA expression and the formation of aberrant crypts in colon of rats. Biofactors. 15: 11-26, 2001.
Davis, C.D. and Uthus, E.U. Dietary selenium and arsenic affect DNA methylation in Caco-2 cells and in rats. J. Nutr. 131, 1872, 2001. (Letter).
Finley, J.W. and Davis, C.D. Manganese absorption and retention in rats is affected by the degree of saturation of dietary fat. Biol. Trace Elem. Res. 82: 143-158, 2001.
Finley, J.W. and Davis, C.D. Selenium (Se) from high selenium broccoli is utilized differently than selenite, selenate and selenomethionine, but is more effective in inhibiting colon carcinogenesis. Biofactors, 14, 191-196, 2001.
Finley, J.W., Ip, C., Lisk, D.J., Davis, C.D., Hintze, K.J. and Whanger, P.D. Investigations on the cancer-protective properties of high-Se broccoli. J. Agric. Food. Chem. 49, 2679-2683, 2001.
Harbell, J., Dunkel, V.C., San, R., Seifried, H.E. and Cameron, T.P. 2001 "Gentoxicity of Naphthenate Salts in the Salmonella/Mammalian-Microsome Assay and Mouse Lymphoma TK+/-Assay" Environmental and Molecular Mutatagenesis (in Press).
Kim, Y.S. and Milner J., "Molecular Targets for Selenium in Cancer Prevention", Nutrition and Cancer 40: 50-54, 2001.
Milne, D.B., Davis, C.D. and Nielsen, F.H. Low dietary zinc alters indices of copper function and status in postmenopausal women. Nutrition 17: 701-708, 2001.
Song K, Milner JA 2001 The influence of heating on the anticancer properties of garlic. J Nutr; 131(3):1054S-7S.
Whittaker, P., Seifried, H.E., San, R., Clarke, J., and Dunkel, V.C., 2001 "Genotoxicity of iron chelators in L5178Y Mouse Lymphoma cells" Environmental and Molecular Mutatagenesis 38:347-356.
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2000
Davis, C.D. Diet and Carcinogenesis. In: Vegetables and Herbs in Health Promotion. CRC Press, Boca Raton, Florida, pp. 273-291, 2000.
Davis, C.D., Milne, D.B. and Nielsen, F.H. Changes in dietary zinc and copper affect zinc-status indicators of postmenopausal women, notably, extracellular superoxide dismutase and amyloid precursor proteins. Am. J. Clin. Nutr. 71: 781-788, 2000.
Davis, C.D. and Newman, S. Inadequate dietary copper increases tumorigenesis in the Min mouse. Cancer Lett. 159:57-62, 2000.
Davis, C.D., Uthus, E.O. and Finley, J.W. Dietary selenium and arsenic affect DNA methylation in Caco-2 cells and in rats. J. Nutr. 130:2903-2909, 2000.
Doong H, Price J, Kim YS, Gasbarre C, Probst J, Liotta LA, Blanchette J, Rizzo K, Kohn E. CAIR_1/BAG_3 forms an EGF_regulated ternary complex with phospholipase C_gamma and Hsp70/Hsc70. Oncogene 19: 4385-95, 2000.
Finley, J.W. Davis, C.D. and Feng, Y. Selenium from high-selenium broccoli protects rats from colon cancer. J. Nutr. 130: 2384-2389, 2000.
Greenwald, P., and Milner J. Nutrition: A Major Player in Chronic Diseases. The Chronicle of Higher Education 2000.
Greenwald, P., Milner JA, Clifford CK 2000 Creating a new paradigm in nutrition research within the National Cancer Institute. J Nutr; 130(12):3103-5.
Knowles, L. and Milner, J.A. 2000. Diallyl Disulfide Increases Cyclin B1 Protein Expression, Decreases p34cdc2 Complex Formation and Hyperphosphorylates p34cdc2 in Human Colon Tumor Cells. Carcinogenesis;21(6):1129-34.
Knowles LM, Milner JA 2000. Allyl sulfides modify cell growth. Drug Metabol Drug Interact;17(1-4):81-107.
Nielsen, F.H., Davis, C.D. and Milne, D.B. Low dietary zinc and copper negatively affect plasma and urine indicators of bone health. Proc. N.D. Acad. Sci. 54: 39, 2000.
Penland, J.G., Milne, D.B. and Davis, C.D. Moderately high zinc intake impairs verbal memory of healthy postmenopausal women on a low copper diet. In: Trace Elements in Man and Animals 10, Kluwer Academic/Plenum Publishers, New York, 2000. pp. 1025-1030.
Ross, S.: Functional foods: the Food and Drug Administration perspective. Amer J Clin Nutr. 71(suppl):1735S-1738S, 2000.
Ross, S.A., McCaffery, P.J., Drager, U.C., and De Luca, L.M.: Retinoids in embryonal development.: Physiol Reviews. 80:1021-1054, 2000.
Uthus, E.O., Gao, J., Finley, J.W. , Davis, C.D. and Nielsen, F.H. Selenium status affects arsenic deprivation in rats. Proc. Sixth Intl. Symp. Metal Ions in Biol. and Med. 6: 254-256, 2000.
Contributing Author to Federal Register Publication: Food Labeling: Health Claims: Plant Sterol/Stanol Esters and Coronary Heart Disease. Department of Health and Human Services, Food and Drug Administration, Interim Final Rule. Federal Register 65 (# 175) Friday, September 8, 2000: 54686-54739.
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Publications Archives
Cameron, T.P., Rogers-Back, A.M., Lawlor, T.E., Harbell, J.W., Seifried, H.E., and Dunkel, V.C. 1991. "Gentoxicity of Multifunctional Acrylates in the Salmonella/Mammalian-Microsome Assay and Mouse Lymphoma TK+/-Assay" Environmental and Molecular Mutatagenesis 17:264-271.
Chandrasekharappa S.C., Guru S.C., Manickam P., Olufemi S.E., Collins F.S., Emmert Buck M.R., Debelenko, L.V., Zhuang Z.A., Lubensky I.A., Liotta L.A., Wang Y., Roe B.A., Weisemann J., Boguski M.S., Agarwal S.K., Kester M.B., Kim Y.S., et al., "Positional cloning of the gene for multiple endocrine neoplasia-type 1." Science 276: 404-407, 1997.
Dunkel, V.C. San, R., Harbell, J., Seifried, H.E., and Cameron, T.P. 1992. "Evaluation of the Mutagenicity of an N-nitroso Contaminant of the Sunscreen Padimate O: N-Nitroso-N-methyl-p-aminobenzoic acid, 2-ethylhexyl ester (NPABAO)" Environmental and Molecular Mutatagenesis 20:188-198.
Dunkel, V.C., San, R.H., Seifried, H.E., Whittaker, P., "Gentoxicity of iron compounds in Salmonella typhimurium and L5178Y mouse lymphoma cells." Environmental and Molecular Mutatagenesis 1999;33 (1):28-41.
Kelloff, G.J., Crowell, J.A., Hawk, E.T., Steele, V.E. et al 1996. "Strategy and planning for chemopreventive drug development: clinical development plans II." J. Cell. Biochem. Supplement 25:54-71
Kim Y.S., Burns A.L., Goldsmith P.K., Heppner C., Park S.Y., Chandrasekharappa S.C., Collins F.S., Spiegel A.M., and Marx S.J., "Stable overexpression of MEN 1 suppresses tumorigenicity of RAS." Oncogene 18: 5936-5942, 1999.
Kohn E.C., Jacobs W., Kim Y.S. et al., "Calcium influx modulates expression of matrix metalloproteinase-2 (72 kDa type IV collagenase, gelatinase A)." J. Biol. Chem. 269: 21505-21511, 1994.
Seifried, H.E., 1986. "Eye Irritation Testing: Historical Perspectives and Future Directions." J. Toxicol. - Cutaneous and Occular Toxicol. 5(2): 89-114.
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Presentations by Nutritional Science Staff
Diet and Epigenetics (ppt, 4.10MB), Sharon Ross Ph.D., M.P.H.
Tea and Tea Polyphenols in Cancer Prevention (ppt, 5.23MB), Sharon Ross Ph.D., M.P.H.
RFA CA-04-004 and CA-03-003: Molecular Targets For Nutrients In Prostate Cancer Prevention (ppt, 56KB), Young S. Kim, Ph.D.
RFA CA-03-016: Diet, DNA Methylation and Other Epigenetic Events, and Cancer Prevention (ppt, 1.06MB)
RFA CA-03-001: Collaborations on Nutritional Modulation of Genetic Pathways Leading to Cancer (ppt, 108KB), J.A. Milner, Ph.D.
Minutes from the U54 Application Briefing (pdf, 18KB)
Questions from the U54 Application Briefing (pdf, 17KB)
Genomics, Nutritional and the Real World (ppt, 9.14MB), J.A. Milner, Ph.D.
Diet and Functional Foods: Inhibitors of the Cancer Process? (ppt, 1.86MB), Harold Seifried, Ph.D.
Life After Graduate School: Working in Government March 31, 2001 (ppt, 1.18MB), Sharon Ross, Ph.D.
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Evidence Based Reviews
These documents are issued by the Food and Nutrition Board of the Institute of Medicine, National Academy of Sciences. The Food and Nutrition Board addresses issues of safety, quality, and adequacy of the food supply; establishes principles and guidelines of adequate dietary intake; and renders authoritative judgments on the relationships among food intake, nutrition, and health.
Reports
Calcium and Related Nutrients
Folate and Other B Vitamins
Antioxidants and Related Nutrients
Trace Elements (e.g., Vitamins A and K, iron and zinc)
Macronutrients (e.g., protein, fat and carbohydrates)
Water and Electrolytes (e.g., potassium, sodium, chloride)
The Effects of Omega-3 Fatty Acids on Cancer (AHRQ report)
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