Vitamin D and Cancer Prevention: Shining Light on the Current Research
Friday, December 02, 2011
12:00 – 1:30 pm EST
Dietary Guidelines: How Much Is Enough? How Much Is Too Much?
JoAnn E. Manson, MD, MPH, DrPH
Professor of Medicine and the Michael and Lee Bell Professor of Women's Health, Harvard Medical School, Chief, Division of Preventive Medicine, Brigham and Women's Hospital, and member of IOM Committee on Dietary Reference Intakes for Vitamin D and Calcium
JoAnn E. Manson, MD, DrPH, is Professor of Medicine and the Michael and Lee Bell Professor of Women's Health at Harvard Medical School, Chief of Preventive Medicine at Brigham and Women's Hospital (BWH), and co-Director of the Connors Center for Women's Health and Gender Biology at BWH. She holds an AB, MPH and DrPH from Harvard University and an MD from Case Western Reserve University School of Medicine. She is a lead investigator on several landmark women's health studies including the Women's Health Initiative and the Harvard Nurses' Health Study, as well as Principal Investigator of the newly launched VITamin D and OmegA-3 TriaL (VITAL). Dr. Manson was a member of the 2010 IOM committee that released new dietary reference intakes for vitamin D and calcium. The focus of Dr. Manson's research has been randomized prevention trials, translational research, and the role of lifestyle factors and nutrition in the prevention of cardiovascular disease and cancer. ScienceWatch ranked Manson as one of the most-cited researchers in clinical medicine. She has received many awards, including the "Woman in Science" Award from the American Medical Women's Association in 2003, Harvard College's Women's Professional Achievement Award" in 2006, the North American Menopause Society's "Postmenopausal Cardiovascular Health Research Award" in 2007, the International Menopause Society's "Henry Burger Research Prize" in 2008, and the American Heart Association's Population Research Prize in 2010 and Distinguished Scientist Award in 2011. She is the current President of the North American Menopause Society. Dr. Manson was elected into membership of the Association of American Physicians in 2005, fellowship in the American Association for the Advancement of Science in 2007, and membership in the Institute of Medicine in 2011.
Clinical Research: Does Vitamin D Inhibit Cancer? How Strong Is the Clinical Evidence?
Donald L. Trump, MD, FACP
President, CEO and Professor of Oncology at Roswell Park Cancer Institute
Donald L. Trump, MD, FACP, is President and CEO of the NCI-designated Comprehensive Cancer Center, Roswell Park Cancer Institute in Buffalo, NY, and Professor of Oncology at Roswell Park Cancer Institute. He holds a MD from Johns Hopkins University School of Medicine. Between 1970 and 1975, he served as resident in internal medicine at The Johns Hopkins Hospital and was chief resident on the Osler Medical Service in 1975. Dr. Trump has held leadership positions in comprehensive cancer centers at Duke University and the University of Pittsburgh. Dr. Trump conducts research on multiple aspects of Vitamin D and cancer prevention. He has worked on research focusing on: high dose vitamin D as a cancer therapeutic, vitamin D insufficiency in cancer patients, and the role of vitamin D supplementation in cancer prevention and morbidity reduction. He is a diplomat of the American Board of Internal Medicine and is past secretary/treasurer of the American Society of Clinical Oncology . Dr. Trump is also on the Editorial Board of HemOnc Today, Urologic Oncology and Oncology.
Basic Science: Potential Mechanisms for Vitamin D-Mediated Effects on Cancer Risk
James C. Fleet, PhD
Professor, Department of Nutrition Science, Center for Cancer Research, Purdue University
James C. Fleet, PhD, is a Professor in the Department of Nutrition Science, the Director of the Interdepartmental Nutrition Program for graduate training in nutrition at Purdue University, and a member of the Purdue University Center for Cancer Research. He holds a BS and PhD from Cornell University and has previously held faculty appointments at Tufts University and the University of North Carolina at Greensboro. Dr. Fleet's research is focused on the molecular and physiological functions of vitamin D as they pertain to the control of calcium metabolism and the prevention of cancer. He uses the tools of molecular biology, genomics, and genetics to address questions relevant to human health and disease. His research is currently funded by two grants from the National Institutes of Health and a grant from the American Institute for Cancer Research (AICR) . He has served as a contributing editor to Nutrition Reviews, on the editorial board of The Journal of Nutrition, and as a member of the INMP study section at NIH. He has been an organizer of FASEB Summer Conferences, on the Program Committee for International Workshops on Vitamin D, and he has been an invited to speak on his work across the globe. In 2001, he was the recipient of the Mead Johnson Award from the American Society for Nutrition , an award that honors achievement in nutrition research during the first 10 years of an independent career. In 2004 he was honored as a "University Faculty Scholar" by Purdue University.
Vitamin D Overview: What Do We Know? What Do We Need to Know?
Gabriela Riscuta, MD, CNS
Nutritionist, Nutritional Science Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health
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